The Lithuanian Jewish Communities Collection is comprised of documents relating to Jewish cultural, religious, social, political, and economic life in approximately 150 towns in Lithuania. The bulk of the collection pertains to the period between 1919 and 1926, when elements of a system of Jewish national autonomy existed within the Lithuanian state, including a Ministry of Jewish Affairs and governmentally empowered Jewish community councils. Smaller parts of the collection relate to the periods before (1860-1918) and after (1927-1940) the autonomy.

This collection consists of materials relating to Jewish life in countries around the world from 1778-1957. Topics include cultural and educational organizations, political parties and elections, charitable institutions, labor, and religious life.

The Vilna Collection represents fragmentary materials that were part of the original YIVO Archives in Vilna before WWII. The collection includes a wide array of materials dealing with a great variety of aspects of Jewish life in the Pre-revolutionary Russian Empire and post-revolutionary Poland, Ukraine, Lithuania, and Soviet Russia. The Collection consists of personal correspondence, official correspondence with organizations and governmental institutions, financial and statistical reports, minutes of meetings of Jewish communal and political organizations, bibliographic materials, including card catalogues and bibliographies. Also included here are vital documents, such as birth certificates and birth registers, affidavits, certificates, diplomas, and travel documents. Additionally, there are petitions, resolutions, appeals, printed materials, manuscripts, lists, and questionnaires. There is a wealth of materials dealing with Jewish book trade and publishing, youth and sports organizations, education, Jewish communal life, and political activities.