This record group contains materials related to the local units of Hadassah—groups, chapters, regions, and co-ops—as well as Junior Hadassah, a youth organization that functioned as a group within the Hadassah Chapter structure. The record group documents over one hundred years of Hadassah’s growth, and illuminates a century of American Jewish communal life, particularly that of Jewish women, across the United States. The record group reflects the formation, administration and activities of the individual groups, chapters, co-ops and regions, and contains information on local events and programs organized around fundraising, Zionism, Jewish heritage, religion and holidays celebration, the study of Hebrew and Yiddish, women's issues, fashion, health, technology and many other topics.

This collection of mainly anti-Semitic material was compiled by a Jewish librarian of German descent who infiltrated the pro-Nazi community developing in New York City in the years leading up to World War II. The bulk of the collection consists of publications and printed matter, with the notable exception of narrative reports that describe first-hand experiences and observations of Nazi-affiliated events. Document types include advertisements, event announcements, books, clippings, correspondence, magazines and newspapers, travel guides, political memorabilia, and other print ephemera.

Hadassah Functions and Operations Records represent the bulk of aid and services provided to Hadassah's membership, from the 1920s to 2011. Materials found in the record group include correspondence, clippings, press releases, manuals and kits for chapters and members to implement programming and chapter structure, fundraising campaigns, scripts, study guides, programming for local and national meetings, biographical files, and training documentation. Departments documented in the record group include Public Affairs, Education, Women's Health, American Affairs, Zionist and International Affairs, Speakers Bureau, Fundraising, Program, Organization, Outreach and Tourism Departments. Materials related to the general administration of Hadassah are also in the record group; these materials include research and development of projects, archives department correspondence and other materials, Hadassah House administration, and strategic planning. The record group also documents Hadassah's efforts to expand membership outside of the United States, by the development of Hadassah International.

The National Committee for Labor Israel (NCLI) was an American fundraising organization closely associated with Israel’s federation of labor and trade unions (Histadrut). NCLI provided financial support for the Histadrut’s educational, health, and social programs in Israel through national and regional solicitation campaigns. Major donors included Labor Zionist organizations, American labor unions, and other Jewish community associations. Financial problems eventually led to the dissolution of NCLI, and the bulk of this collection documents its final decades of operation. A large portion of the records pertain to development projects in Israel during the 1960s -1970s.