The collection documents American Jewish Committee’s efforts to combat all forms of discrimination against the Jews in the United States. Additionally, there are materials pertaining to AJC’s work regarding other minority groups in the United States. The collection offers researchers a unique chance to see how and what was done prior to the changes in public opinion and civic and legal laws. The American Jewish Committee Records, Subject Files consists of materials created by executive offices, departments, local offices and chapters of the Committee concerning a variety of matters; foremost Jewish civil and religious rights, immigration, and the Holocaust.

This collection consists of general reference files from the New York City headquarters of the American Jewish Committee (AJC). Materials originated in various AJC departments and were maintained by a Central Records office until 1962, when records retention policy was decentralized. Document types include correspondence, memoranda, reports, clippings, and published materials concerning individuals, businesses, government agencies, and other organizations related to the work of the AJC.

The collection contains the records of the Jewish Defense League (JDL), a militant Zionist organization with a stated goal to protect Jews from all forms of antisemitism. The materials document the origins of the JDL, the organization's mission statement and recruitment strategies and account for its most definitive actions. The collection also reflects the League's turbulent relationship with, and its criticism of the mainstream Jewish agencies, as well as examples of criticism of the League's controversial methods from various sources. The collection prominently covers the JDL's role as a pioneer of the American Soviet Jewry movement. Materials on the 1971 World Conference of Jewish Communities are also included. The documents include the Articles of the Organization, correspondence and press releases, membership and recruitment materials, newsletters, newspaper clippings and ephemera.