The Annual and Mid-Winter National Conventions Records document the proceedings and outcomes of the conventions and conferences attended by Hadassah’s National Board as well as by convention delegates from the various regions of Hadassah. The conventions in particular are where local and regional leaders meet with each other and the National Board and learn about Hadassah’s various projects and committees. This record group also includes annual reports from 1926-2001.

This record group contains materials related to the local units of Hadassah—groups, chapters, regions, and co-ops—as well as Junior Hadassah, a youth organization that functioned as a group within the Hadassah Chapter structure. The record group documents over one hundred years of Hadassah’s growth, and illuminates a century of American Jewish communal life, particularly that of Jewish women, across the United States. The record group reflects the formation, administration and activities of the individual groups, chapters, co-ops and regions, and contains information on local events and programs organized around fundraising, Zionism, Jewish heritage, religion and holidays celebration, the study of Hebrew and Yiddish, women's issues, fashion, health, technology and many other topics.

Hadassah Functions and Operations Records represent the bulk of aid and services provided to Hadassah's membership, from the 1920s to 2011. Materials found in the record group include correspondence, clippings, press releases, manuals and kits for chapters and members to implement programming and chapter structure, fundraising campaigns, scripts, study guides, programming for local and national meetings, biographical files, and training documentation. Departments documented in the record group include Public Affairs, Education, Women's Health, American Affairs, Zionist and International Affairs, Speakers Bureau, Fundraising, Program, Organization, Outreach and Tourism Departments. Materials related to the general administration of Hadassah are also in the record group; these materials include research and development of projects, archives department correspondence and other materials, Hadassah House administration, and strategic planning. The record group also documents Hadassah's efforts to expand membership outside of the United States, by the development of Hadassah International.

The Lipsky Family Papers reflect the professional and personal activities of Eleazar Lipsky (1911-1993), his father, Zionist leader Louis Lipsky (1876-1963), and his mother, Charlotte Lipsky (1879-1959), as well as other family members. Eleazar Lipsky was a lawyer, novelist, Zionist and the head of the Jewish Telegraphic Agency in the early 1960s. While working on a multi-part family novel, Eleazar Lipsky gathered and arranged much of the family material in this collection. In addition to family history, the collection contains information on the American Zionist movement, Bernard Richards’s role in the Committee of Jewish Delegations at the 1919 Paris Peace Conference, and various legal battles involving such parties as the Jewish Week, the American Examiner, Doubleday, Philip Hochstein and Lillie Shultz. The materials include correspondence, an unfinished manuscript, legal transcripts, clippings, speeches, research materials, financial documents, miscellaneous writings and a few photographs.

This collection contains the personal and professional papers of William Edlin, editor of The Day and a prominent Socialist. It includes correspondence with individuals and with organizations, newspaper clippings, manuscripts of works by Edlin and by others as well as translations done by Edlin, and some of Edlin’s personal documents. These materials relate to Edlin’s involvement with The Day, with the Socialist Party, the Workmen’s Circle, various labor and Zionist organizations, literary clubs and activities, and with music, art and drama.

Young Judaea is the oldest Zionist youth organization in the United States, established as a national organization in 1909 by the Federation of American Zionists. It was supported by Hadassah, including direct financial sponsorship from 1967-2011. The major aims of Young Judaea throughout its history have been to advance the cause of Zionism, to further the mental, moral, and physical development of Jewish youth, and to promote Jewish culture and ideals in accordance with Jewish traditions. Young Judaea has remained non-partisan and non-denominational, embracing and recruiting Jewish youth from all backgrounds.

The Youth Aliyah Records in the Hadassah Archives document Hadassah's work with multiple international organizations to rescue Jewish children from continental Europe to Palestine from 1933-1945. The collection also documents Hadassah's involvement with Youth Aliyah since 1946 in providing residential, educational, vocational, rehabilitative and therapeutic care for displaced and at-risk youth from around the world.