The Annual and Mid-Winter National Conventions Records document the proceedings and outcomes of the conventions and conferences attended by Hadassah’s National Board as well as by convention delegates from the various regions of Hadassah. The conventions in particular are where local and regional leaders meet with each other and the National Board and learn about Hadassah’s various projects and committees. This record group also includes annual reports from 1926-2001.

This record group contains materials related to the local units of Hadassah—groups, chapters, regions, and co-ops—as well as Junior Hadassah, a youth organization that functioned as a group within the Hadassah Chapter structure. The record group documents over one hundred years of Hadassah’s growth, and illuminates a century of American Jewish communal life, particularly that of Jewish women, across the United States. The record group reflects the formation, administration and activities of the individual groups, chapters, co-ops and regions, and contains information on local events and programs organized around fundraising, Zionism, Jewish heritage, religion and holidays celebration, the study of Hebrew and Yiddish, women's issues, fashion, health, technology and many other topics.

This record group includes documents created and maintained by the Office of the President, the Office of the Executive Director and the Chair of the Division Coordinators/Directors Committee. Prominent is the Henrietta Szold series, containing correspondence by and to Szold as well as printed materials written by and about her. The files in this record group were created by a national president or executive director, or for their use, or maintained in their office during their years in office. Included are correspondence, minutes, memos, publications, reports and subject files on topics with which these individuals were involved.

Young Judaea is the oldest Zionist youth organization in the United States, established as a national organization in 1909 by the Federation of American Zionists. It was supported by Hadassah, including direct financial sponsorship from 1967-2011. The major aims of Young Judaea throughout its history have been to advance the cause of Zionism, to further the mental, moral, and physical development of Jewish youth, and to promote Jewish culture and ideals in accordance with Jewish traditions. Young Judaea has remained non-partisan and non-denominational, embracing and recruiting Jewish youth from all backgrounds.

The Youth Aliyah Records in the Hadassah Archives document Hadassah's work with multiple international organizations to rescue Jewish children from continental Europe to Palestine from 1933-1945. The collection also documents Hadassah's involvement with Youth Aliyah since 1946 in providing residential, educational, vocational, rehabilitative and therapeutic care for displaced and at-risk youth from around the world.