The United States Holocaust Memorial Museum was created to advance and disseminate knowledge about the Holocaust, to document and interpret Holocaust history, and to serve as the nation's permanent living memorial to the Holocaust. The collection includes newsletters, Days of Remembrance for the Victims of the Holocaust publications and printed matter, photographs, press releases, conference material, teaching guides and curricula, and fundraising and membership material.

William Korey Papers document life and works of a prominent human rights expert who played a leadership role in the American Soviet Jewry movement. Dr. Korey served as a regional director of Anti-Defamation League and later as a founding director of B'nai Brith International's U.N. office which worked on the problem of discrimination faced by the Jews in the Soviet Union. Dr. Korey was deeply involved in the processes pivotal to the success of the Sovet Jewry movement, such as the defense of the Helsinki Accords and the adoption of the Jackson-Vanik amendment. Parallel to his work on behalf of Soviet Jewry Dr. Korey participated in the efforts to realize the U.S. ratification of the genocide treaty that eventually came to fruition in 1988. William Korey authored hundreds of articles and essays and a number of books on the subjects related to the Jews in the Soviet Union. He taught at the Long Island University, City College of New York, Columbia University, Brooklyn College and several other major universities. The William Korey papers include materials from the late 1940s through 2010, and the bulk of the collection is dated 1970s-1990s. The documents include manuscripts, correspondence, notes, publications, news clippings, photographs and a data CD.

Young Judaea is the oldest Zionist youth organization in the United States, established as a national organization in 1909 by the Federation of American Zionists. It was supported by Hadassah, including direct financial sponsorship from 1967-2011. The major aims of Young Judaea throughout its history have been to advance the cause of Zionism, to further the mental, moral, and physical development of Jewish youth, and to promote Jewish culture and ideals in accordance with Jewish traditions. Young Judaea has remained non-partisan and non-denominational, embracing and recruiting Jewish youth from all backgrounds.

The Youth Aliyah Records in the Hadassah Archives document Hadassah's work with multiple international organizations to rescue Jewish children from continental Europe to Palestine from 1933-1945. The collection also documents Hadassah's involvement with Youth Aliyah since 1946 in providing residential, educational, vocational, rehabilitative and therapeutic care for displaced and at-risk youth from around the world.