The Elias Tcherikower Collection documents the professional and personal life of Elias Tcherikower, a scholar, communal activist, and one of the founders of the YIVO Institute for Jewish Research, and to a smaller extent personal life of his wife, Riva Tcherikower, née Teplitski. Collected here are Tcherikower’s writings, professional and personal correspondence, photographs, manuscripts by other scholars, research materials, printed materials, financial documents, conference and exhibit materials, minutes of meetings, bibliographic materials and personal materials of Riva Tcherikower, née Teplitski, and Chaim Tcherikower.

Mizrakh Yidisher Historisher Arkhiv Collection consists of diverse materials that pertain to pogroms in the period between 1918 and 1921 that took place mostly in Ukraine but also in Belarus, Poland, and Russia. There is a wide variety of topics that are covered in the collection including Ukrainian-Jewish relations during a short lived Ukrainian Republic, Ukrainian-Jewish political, communal, and governmental organizations, Ukrainian government and the role of politicians and military Commanders in pogroms, most notably Symon Petlyura and Ataman Grigoriev, pogroms and its aftermath, military occupation of Ukraine by the German, Polish, Bolshevik and General Denikin’s armies and its relationship to pogroms, Jewish self-defense and relief work. Also included here are materials pertaining to the trial of Sholom Schwarzbard who was tried in France for assassination of Symon Petlyura. The collection consists of of large amount of lists and eyewitness testimonies, correspondence, complaints and petitions, reports and resolutions, statements and proclamations, memoranda and circular letters, conference materials, statues and by-laws, clippings and bulletins, military orders, and photographs.

The Marc Ratner Papers consist of materials pertaining to Marc Ratner's political activities as one of the leaders of the SERP (Sotsialisticheskaya Yevreyskaya Rabochaya Partiia, Jewish Socialist Workers' Party, Rus: Социалистическая еврейская рабочая партия) which was a left leaning Zionist revolutionary party. The collection consists of correspondence, circular letters, clippings, minutes of meetings, essays, manuscripts, political resolutions and statements. The bulk of the collection consists of correspondence between party members, minutes of meetings and manuscripts.

The Rabbinical School and Teachers’ Institute in Vilna was one of two Jewish state schools established in the Russian Empire in 1847 to train state appointed (kazënnye) rabbis and teachers for Jewish elementary state schools in the Pale of Settlement. The purpose of these schools was to undermine and replace the traditional kheder system of education. The other such school was in Zhitomir. The state schools were unpopular because of their assimilationist policies. The Vilna Rabbinical School was closed in 1873, but the Teachers' Institute remained in existence until 1914

The May Cohn Russia and Soviet Union Collection (Vilna Archives) includes materials dealing with a wide range of topics mostly pertaining to Jewish life in the Russian Empire and the Soviet Union and to a smaller extent to everyday life of ordinary Russian citizens. The collection consists of official government documents such as reports, decrees and regulations, circular letters, lists, vital records, Census records, residency and emigration permits. Also included here are manuscripts, correspondence, printed materials, petitions, announcements, posters, questionnaires, and minutes of meetings. Materials collected here shed light on the way Jewish religious and civil life was administered in the Russian Empire and the Soviet Union.