The American Federation of Jews from Central Europe Collection consists of the Federation’s office files. This includes professional correspondence, by-laws, materials related to meetings and lectures, newspaper clippings, photographs, meeting minutes, reports, speeches, drafts, financial records, legal documents and forms, materials related to immigration and naturalization, newsletters and circulars, membership records, personnel files, restitution materials, oral history transcripts, and items of various related organizations and synagogues. There are also some personal documents sent to the AFJCE by members of the public.

The Brüder Böhm Company Collection includes materials documenting the operations of the company that was involved in the production of hats and had plants in Vienna, Austria and Neutitschein, Czechoslovakia (now Nový Jicín, Czech Republic). There is also a small amount of personal materials pertaining to the lives of the owners of the company, the brothers Joseph and Victor Böhm and their cousin Richard Böhm, as well as some other members of the Böhm family.

The Guido Kisch Collection documents the life and professional activities of Guido Kisch, teacher, researcher, and scholar in the field of Legal History. It also documents personal and to a lesser degree professional lives of some of the other members of the Kisch family, most notably his brother, Bruno Kisch, a cardiologist, and their father, Alex Kisch, who was a rabbi and a writer. The collection includes brochures, booklets, clippings, correspondence, financial documents, minutes, notes, off prints, photographs, printed materials, and writings.

Papers of Hans Kohn (1891-1971), historian and lawyer, who was active in Zionist organizations. He published extensively on questions of nationalism and related topics. The collection consists of documents relating to Hans Kohn's professional experience, materials relating to his political activities, correspondence, diaries, materials relating to his experience in World War I and as a prisoner of war, personal documents, photos, clippings.

This collection consists of photographs and negatives of World ORT conferences and congresses, various individuals connected with ORT, and ORT vocational programs and activities, including in Displaced Person’s camps, in Europe, Asia, the Middle East, Africa, Cuba, and North and South America.

This collection contains the personal and professional papers of Isaac Nachman Steinberg, a Russian-Jewish political writer, leader of the Left Socialist Revolutionary Party during the 1917 revolution in Russia, People’s Commissar of Justice in the first Bolshevik government, leader of the Jewish Territorialist Movement and of the Freeland League for Jewish Territorial Colonization, and a founding member of the YIVO Institute in Vilna. These materials include Steinberg’s writings, personal correspondence, clippings, journals, meeting announcements, and some photographs. These materials relate mainly to Steinberg’s work with the Freeland League and plans for the large-scale settlement of Jews in various places around the world.

This collection contains the personal and professional papers of William Edlin, editor of The Day and a prominent Socialist. It includes correspondence with individuals and with organizations, newspaper clippings, manuscripts of works by Edlin and by others as well as translations done by Edlin, and some of Edlin’s personal documents. These materials relate to Edlin’s involvement with The Day, with the Socialist Party, the Workmen’s Circle, various labor and Zionist organizations, literary clubs and activities, and with music, art and drama.

The Renate Bridenthal Family Collection primarily documents the lives and especially the emigration experiences of Renate Bridenthal's parents, Elchunon and Irene Rubin. Papers of Irene Rubin are prominent in the collection and include restitution correspondence and her writing. Documents related to Renate and her brother Harribald's early lives and emigration is are also present. The collection consists of extensive personal and restitution correspondence, official documents, newspaper clippings regarding Irene Rubin's death, drafts of her writing, and three albums.