The records of the American Jewish Historical Society, the oldest national ethnic historical organization in the United States, include correspondence of officers and staff as well as inter-office memos, multiple versions of the constitution and by-laws of the society, meeting minutes of administrative branches and committees, membership and financial records, reports, exhibit materials, records relating to the society’s library and archival holdings, press releases and newspaper clippings, and publications and newsletters created by the society. There are also materials from various programs, such as meetings and conferences, tours, lectures, awards and dinners, films, and educational programs.

The Annual and Mid-Winter National Conventions Records document the proceedings and outcomes of the conventions and conferences attended by Hadassah’s National Board as well as by convention delegates from the various regions of Hadassah. The conventions in particular are where local and regional leaders meet with each other and the National Board and learn about Hadassah’s various projects and committees. This record group also includes annual reports from 1926-2001.

This collection is comprised of correspondence and financial documents from and to the Central Committee Knesseth Israel Charity of Rabbi Maier Baal Haness from 1924 through 1950. The charity was a Jewish charity formed in 1924 in both Israel and the state of New York with the purpose of collecting contributions to help the state of Israel and American Jews. The collection contains charity donation records from 1924 through 1950.

This record group contains materials related to the local units of Hadassah—groups, chapters, regions, and co-ops—as well as Junior Hadassah, a youth organization that functioned as a group within the Hadassah Chapter structure. The record group documents over one hundred years of Hadassah’s growth, and illuminates a century of American Jewish communal life, particularly that of Jewish women, across the United States. The record group reflects the formation, administration and activities of the individual groups, chapters, co-ops and regions, and contains information on local events and programs organized around fundraising, Zionism, Jewish heritage, religion and holidays celebration, the study of Hebrew and Yiddish, women's issues, fashion, health, technology and many other topics.

Hadassah Functions and Operations Records represent the bulk of aid and services provided to Hadassah's membership, from the 1920s to 2011. Materials found in the record group include correspondence, clippings, press releases, manuals and kits for chapters and members to implement programming and chapter structure, fundraising campaigns, scripts, study guides, programming for local and national meetings, biographical files, and training documentation. Departments documented in the record group include Public Affairs, Education, Women's Health, American Affairs, Zionist and International Affairs, Speakers Bureau, Fundraising, Program, Organization, Outreach and Tourism Departments. Materials related to the general administration of Hadassah are also in the record group; these materials include research and development of projects, archives department correspondence and other materials, Hadassah House administration, and strategic planning. The record group also documents Hadassah's efforts to expand membership outside of the United States, by the development of Hadassah International.

This record group contains meeting minutes, correspondence and reports of the Hadassah Council in Israel (originally the Hadassah Emergency Services and the Hadassah Council in Palestine), the Hadassah Youth Services (originally the Palestine Council of Hadassah) and the Hadassah Youth Services (HYS) successor organizations, Hadassah Vocational Education Services (HVES) and Hadassah Israel Education Services (HIES). The records represent the activities of Hadassah's representatives in Palestine/Israel, from 1927 to the 1990s. The Hadassah Youth Services focused on providing services to underserved youth in Palestine/Israel, most notably with their school luncheon and Guggenheimer playground programs. After HYS changed its working name to HVES in 1952, it began to focus on vocational education projects in Israel. Legally, however, the name of the organization in Israel remained Hadassah Youth Services. The Hadassah Council in Israel acted as an advisor and liaison between Hadassah's American offices and Hadassah's Israel projects, including the Hadassah Medical Organization, Youth Aliyah, and Hadassah Youth Services.

The Hadassah Medical Organization Records in the Hadassah Archives document Hadassah's work in providing health care resources in Palestine/Israel since 1918. The activities documented revolve around the development of the Hadassah Hospital; health centers; dental centers; occupational and rehabilitative services; medical, nursing, dental, and pharmacy schools; as well as numerous educative and preventive projects, especially those aimed at infant care. The documents also reflect the history of the Yishuv (Jewish settlement in Palestine) and the establishment of the State of Israel. The record group contains articles, clippings, correspondence, financial records, fundraising material, minutes, personal accounts, press releases, publicity material, reports, and statistical reports.

The Joseph Shubow Collection documents the life and professional activities of Joseph Shubow, military Chaplain, leader of the Congregation B’nai Moshe, Boston, MA and a prominent American Zionist leader. The collection includes correspondence, documents, lists, writings, speeches and sermons notes, photographs, and printed materials. Materials constituting the collection reflect various aspects of Joseph Shubow’s personal and professional life, religious leadership and writings in the fields of Judaism and Jewish history.

The Lipsky Family Papers reflect the professional and personal activities of Eleazar Lipsky (1911-1993), his father, Zionist leader Louis Lipsky (1876-1963), and his mother, Charlotte Lipsky (1879-1959), as well as other family members. Eleazar Lipsky was a lawyer, novelist, Zionist and the head of the Jewish Telegraphic Agency in the early 1960s. While working on a multi-part family novel, Eleazar Lipsky gathered and arranged much of the family material in this collection. In addition to family history, the collection contains information on the American Zionist movement, Bernard Richards’s role in the Committee of Jewish Delegations at the 1919 Paris Peace Conference, and various legal battles involving such parties as the Jewish Week, the American Examiner, Doubleday, Philip Hochstein and Lillie Shultz. The materials include correspondence, an unfinished manuscript, legal transcripts, clippings, speeches, research materials, financial documents, miscellaneous writings and a few photographs.

The collection documents the National Jewish Welfare Board's (JWB) evolution from an organization founded in 1917 to provide support for soldiers in times of war to an agency involved in all aspects of Jewish life both in the United States and abroad. In 1990 JWB recreated itself as the Jewish Community Centers Association of North America.

The Robison Family Fapers reflect various activities of Adolf C. and Ann Green Robison in civic organizations, Jewish communal life, Jewish national and international affairs, and individually in the arts. The collection contains information on the origins of the United Nations; and on aid to Israel before, during, and after the War of Independence. The materials include correspondence, memoranda, minutes, reports, financial documents, newspaper clippings, photographs, diaries, scrapbooks, musical scores, and play scripts.

Young Judaea is the oldest Zionist youth organization in the United States, established as a national organization in 1909 by the Federation of American Zionists. It was supported by Hadassah, including direct financial sponsorship from 1967-2011. The major aims of Young Judaea throughout its history have been to advance the cause of Zionism, to further the mental, moral, and physical development of Jewish youth, and to promote Jewish culture and ideals in accordance with Jewish traditions. Young Judaea has remained non-partisan and non-denominational, embracing and recruiting Jewish youth from all backgrounds.

The Youth Aliyah Records in the Hadassah Archives document Hadassah's work with multiple international organizations to rescue Jewish children from continental Europe to Palestine from 1933-1945. The collection also documents Hadassah's involvement with Youth Aliyah since 1946 in providing residential, educational, vocational, rehabilitative and therapeutic care for displaced and at-risk youth from around the world.