The Adolf Loebel Collection primarily documents the events of the Holocaust in Baden-Württemberg with an extensive amount of newspaper clippings. To a smaller extent it shows a few of the experiences of Adolf Loebel, head of the Jewish community in Heidelberg. In addition to the many newspaper clippings the collection contains circular letters and announcements, some correspondence, a list of Jews in Baden from 1940 and a few photographs.

The majority of the materials in this collection consist of original and some published documents pertaining to the Berlin physician Curt Bejach and his family. Also included are original correspondence and published articles about the physicist Samuel Goudsmit.

The collection contains contains various materials pertaining to Eugen (Yitzhak) Neter, collected by Shlomo Marcus.

This collection contains photocopies of documents, photographs, and genealogical tables pertaining to the family of Evelyn Pearl (Perl) of Berlin and the related Wachsmann (Waxman) and Heimann families.

The collection consists of material pertaining to Rabbi Leo Baeck. The material, mostly secondary, was collected by the Leo Baeck Institute’s staff and in some cases bear markings and notes by the Institute’s staff.

The Helen and Eva Hesse Collection holds material on the Hesse family of Hamburg. Most notable in this collection are the diaries of Helen and Eva Hesse, created by Wilhelm Hesse, which document the sisters' childhood. In addition, the collection includes scrapbooks and photograph albums, some of Wilhelm Hesse's educational papers, and correspondence related to immigration.

This collection documents the lives of the Marx family, who lived at the beginning of the twentieth century in Ludwigshafen am Rhein (Rheinland-Pfalz), Germany. There Sigmund Marx built up a flour wholesale business with his brother Willy Marx. Sigmund Marx was married to Mathilde Marx, who gave birth to Ernest and Paul Marx. The collection contains the correspondence of the Marx family, financial papers of the Sigmund Marx business and a huge amount of clippings regarding German-Jewish life during the Nazi period.

The collection holds various documents pertaining to the Michelsohn family, originally from the town of Hausberge (Minden, Westphalia). These include vital records, a genealogical table, as well as clippings and publications.

The collection contains documentation of the life of Moritz Schweizer, particularly his persecution during World War II. Included in the collection is a diary excerpt listing concentration camp victims he buried after his liberation; correspondence; documents pertaining to his emigration from Germany to Amsterdam; documents pertaining to his internment in Westerbork and Bergen-Belsen; information kept by Schweizer on children in the orphanage at Bergen-Belsen; and letters of sympathy to his wife after his death.

The Paul Egon Cahn Collection holds personal and official papers of Paul Egon and Senta Ilse Cahn and their families, as well as about one thousand personal and family photographs.

The Rose Lehrberger Grossmann Collection holds papers and correspondence of Rose Grossmann and her husband Emil Grossmann. The collection contains immigration documentation, letters and official papers reflecting the attempt to get visas for Rose's parents as well as documents related to Rose and Emil Grossmann's restitution claims.

This collection consists primarily of photocopies, largely of materials pertaining to memorial and reconciliation events for the Jewish community of Schermbeck in the 1980s.

This collection documents the lives of Vera Meyer's family members, especially her parents, Alfred and Eva Meyer, but also involving her grandparents and uncles. Prominent in the collection are the many family photographs and copies of family correspondence, including immigration and wartime letters. Other material consists of some biographical essays and a family tree.

The collection documents Willy Nordwind’s efforts to bring as many German Jews as possible out of Germany before World War II. Included here is correspondence with those who had arrived or those whom Willy Nordwind was still trying to bring over.