The Annual and Mid-Winter National Conventions Records document the proceedings and outcomes of the conventions and conferences attended by Hadassah’s National Board as well as by convention delegates from the various regions of Hadassah. The conventions in particular are where local and regional leaders meet with each other and the National Board and learn about Hadassah’s various projects and committees. This record group also includes annual reports from 1926-2001.

This record group includes documents created and maintained by the Office of the President, the Office of the Executive Director and the Chair of the Division Coordinators/Directors Committee. Prominent is the Henrietta Szold series, containing correspondence by and to Szold as well as printed materials written by and about her. The files in this record group were created by a national president or executive director, or for their use, or maintained in their office during their years in office. Included are correspondence, minutes, memos, publications, reports and subject files on topics with which these individuals were involved.

Hadassah Functions and Operations Records represent the bulk of aid and services provided to Hadassah's membership, from the 1920s to 2011. Materials found in the record group include correspondence, clippings, press releases, manuals and kits for chapters and members to implement programming and chapter structure, fundraising campaigns, scripts, study guides, programming for local and national meetings, biographical files, and training documentation. Departments documented in the record group include Public Affairs, Education, Women's Health, American Affairs, Zionist and International Affairs, Speakers Bureau, Fundraising, Program, Organization, Outreach and Tourism Departments. Materials related to the general administration of Hadassah are also in the record group; these materials include research and development of projects, archives department correspondence and other materials, Hadassah House administration, and strategic planning. The record group also documents Hadassah's efforts to expand membership outside of the United States, by the development of Hadassah International.

The Hadassah Archives documents the activities of Hadassah, the Women's Zionist Organization of America. Founded in 1912, the organization engaged hundreds of thousands of American Jewish women in the Zionist project. Materials include extensive records of its social welfare projects in Palestine and later Israel, such as Youth Aliyah and the Hadassah Medical Organization. Administrative records document the organization's governance, operations, and functions. The collection also includes the papers of Hadassah founder, Henrietta Szold, as well as the organization's national presidents, executive directors, and other important individuals. Additional materials also document Hadassah's organizational activity in the United States such as annual and midwinter conventions and the dozens of active local chapters from all over the United States. Hadassah maintained an active publishing schedule, and the records include hundreds of published newsletters, flyers, and magazines. Other materials include thousands of photographs, extensive audiovisual material, and hundreds of artifacts.

The Hadassah Medical Organization Records in the Hadassah Archives document Hadassah's work in providing health care resources in Palestine/Israel since 1918. The activities documented revolve around the development of the Hadassah Hospital; health centers; dental centers; occupational and rehabilitative services; medical, nursing, dental, and pharmacy schools; as well as numerous educative and preventive projects, especially those aimed at infant care. The documents also reflect the history of the Yishuv (Jewish settlement in Palestine) and the establishment of the State of Israel. The record group contains articles, clippings, correspondence, financial records, fundraising material, minutes, personal accounts, press releases, publicity material, reports, and statistical reports.

The records document the Histadruth Ivrit's early history to the present, representing a significant portion of its work in spreading the Hebrew language in the United States in the second half of the twentieth-century. The records include substantial amount of material regarding the organization's history, administration, public events, publications, and reports. Some information of the early history of the Histadruth Ivrit could be found in the records kept by the writer Daniel Persky. Persky collected personal and professional records that include correspondence with friends, readers, and writers; a partial collection of the drafts of his own publications, and a collection of photographs and newspaper clippings. The functions and activities of the Histadruth Ivrit are documented through Board of Trustees and Board meetings agendas and minutes; various programs for events, conventions, conferences, and celebrations; documents related to fundraising; public relations, press releases and brochures; correspondence with different individuals, organizations, and foundations; Histadruth Ivrit's publications among them the newspaper Hadoar and Tov Lichtov; a large collection of photographs, and scrapbooks. The records of the Histadruth Ivrit represent the large majority of the organization's activities dating from the 1980s to the present. Records for the earlier years of activities are fragmented and incomplete. The records related to the life of Daniel Persky are also partial and copies of many of his publications are missing. This collection included brochures, correspondence, financial records, flyers, grant applications, invitations, lists, minutes, news clipping, orders, periodicals, photographs, press releases, reports, and scrapbooks.

Louis Lipsky (1876-1963) was a noted Zionist leader, journalist, and writer. The collection contains personal correspondence, memoranda, speeches, magazine and newspaper articles, manuscripts, drafts of books, and organizational materials concerning the Zionist movement, and various Jewish organizations.

This collection contains Marvin Lowenthal's correspondence, journals, diaries, documents, photographs, memorabilia, and printed materials relating to his life, writings, Zionist activities, and relief work on behalf of German Jewry. Includes material on his youth, school work, and college years, as well as autobiographical writings and family correspondence containing information on Horace Kallen and early 20th century Zionist activities. Of particular note is his later correspondence with Jacob Billikopf, Jerome Frank, Horace M. Kallen, Elmer Rice, Eugene C. Taylor, and Stephen S. Wise.

The Name File record group is a collection of documents representing various individuals, corporations, and non-profit groups who were affiliated with Hadassah. These files were originally arranged alphabetically by the organization's central filing department as a ready reference source on leaders, doctors, speakers, donors, and religious figures associated with Hadassah's many projects. This collection includes correspondence, clippings, newsletters, and other ephemeral documents.

The collection documents the National Jewish Welfare Board's (JWB) evolution from an organization founded in 1917 to provide support for soldiers in times of war to an agency involved in all aspects of Jewish life both in the United States and abroad. In 1990 JWB recreated itself as the Jewish Community Centers Association of North America.

This record group contains personal papers and special collections documenting individuals, both Hadassah members and non-Hadassah members, who were important to Hadassah. Much of the material forming the collections in this record group came from the administrative files of the national office of Hadassah, though some of the material was donated to Hadassah. Key individuals represented within this record group include Hadassah national board members Anna Tulin Elyachar, Bertha S. Schoolman, and Denise Tourover Ezekiel, as well as Jesse Zel Lurie who served as the first professional editor of Hadassah Magazine (originally Hadassah Newsletter) from 1947 to 1980.

This record group consists of printed materials and publications, produced by Hadassah projects and departments, Young Judaea, and other Zionist organizations from 1911-2011. Materials in the record group include periodicals, newsletters, greeting cards, certificates, invitations, brochures, pamphlets, catalogs, and other professionally produced printed materials. Besides Young Judaea, projects documented include Hadassah Magazine, the Hadassah Medical Organization, Youth Aliyah, the Jewish National Fund, and Hadassah Israel Education Services.

The Robison Family Fapers reflect various activities of Adolf C. and Ann Green Robison in civic organizations, Jewish communal life, Jewish national and international affairs, and individually in the arts. The collection contains information on the origins of the United Nations; and on aid to Israel before, during, and after the War of Independence. The materials include correspondence, memoranda, minutes, reports, financial documents, newspaper clippings, photographs, diaries, scrapbooks, musical scores, and play scripts.

The Youth Aliyah Records in the Hadassah Archives document Hadassah's work with multiple international organizations to rescue Jewish children from continental Europe to Palestine from 1933-1945. The collection also documents Hadassah's involvement with Youth Aliyah since 1946 in providing residential, educational, vocational, rehabilitative and therapeutic care for displaced and at-risk youth from around the world.