The materials in the record group mostly consist of reproductions of building plans of the Hadassah hospitals on Mount Scopus and Ein Kerem from the 1920s to the 2000s. Other properties documented in the record group include buildings managed by Youth Aliyah, Hadassah Youth Services, Young Judaea, Hadassah Israel Education Services, the National Office, and the Hadassah Medical Organization. These records document a core Hadassah function, the building of medical and social service facilities in Palestine/Israel.

Hadassah Functions and Operations Records represent the bulk of aid and services provided to Hadassah's membership, from the 1920s to 2011. Materials found in the record group include correspondence, clippings, press releases, manuals and kits for chapters and members to implement programming and chapter structure, fundraising campaigns, scripts, study guides, programming for local and national meetings, biographical files, and training documentation. Departments documented in the record group include Public Affairs, Education, Women's Health, American Affairs, Zionist and International Affairs, Speakers Bureau, Fundraising, Program, Organization, Outreach and Tourism Departments. Materials related to the general administration of Hadassah are also in the record group; these materials include research and development of projects, archives department correspondence and other materials, Hadassah House administration, and strategic planning. The record group also documents Hadassah's efforts to expand membership outside of the United States, by the development of Hadassah International.

The Hadassah Medical Organization Records in the Hadassah Archives document Hadassah's work in providing health care resources in Palestine/Israel since 1918. The activities documented revolve around the development of the Hadassah Hospital; health centers; dental centers; occupational and rehabilitative services; medical, nursing, dental, and pharmacy schools; as well as numerous educative and preventive projects, especially those aimed at infant care. The documents also reflect the history of the Yishuv (Jewish settlement in Palestine) and the establishment of the State of Israel. The record group contains articles, clippings, correspondence, financial records, fundraising material, minutes, personal accounts, press releases, publicity material, reports, and statistical reports.

This collection contains Marvin Lowenthal's correspondence, journals, diaries, documents, photographs, memorabilia, and printed materials relating to his life, writings, Zionist activities, and relief work on behalf of German Jewry. Includes material on his youth, school work, and college years, as well as autobiographical writings and family correspondence containing information on Horace Kallen and early 20th century Zionist activities. Of particular note is his later correspondence with Jacob Billikopf, Jerome Frank, Horace M. Kallen, Elmer Rice, Eugene C. Taylor, and Stephen S. Wise.

The Name File record group is a collection of documents representing various individuals, corporations, and non-profit groups who were affiliated with Hadassah. These files were originally arranged alphabetically by the organization's central filing department as a ready reference source on leaders, doctors, speakers, donors, and religious figures associated with Hadassah's many projects. This collection includes correspondence, clippings, newsletters, and other ephemeral documents.

The collection documents the National Jewish Welfare Board's (JWB) evolution from an organization founded in 1917 to provide support for soldiers in times of war to an agency involved in all aspects of Jewish life both in the United States and abroad. In 1990 JWB recreated itself as the Jewish Community Centers Association of North America.

This collection contains correspondence between Horace M. Kallen and many important individuals and organizations, as well as manuscripts, notes and other materials for speeches, financial documents, research materials, academic records, and various other assorted items. These materials serve to illustrate Kallen’s important role in philosophy, education, religion, and politics and his deep involvement with consumer rights, environmental controls, Jewish issues, and civil liberties.

This record group contains personal papers and special collections documenting individuals, both Hadassah members and non-Hadassah members, who were important to Hadassah. Much of the material forming the collections in this record group came from the administrative files of the national office of Hadassah, though some of the material was donated to Hadassah. Key individuals represented within this record group include Hadassah national board members Anna Tulin Elyachar, Bertha S. Schoolman, and Denise Tourover Ezekiel, as well as Jesse Zel Lurie who served as the first professional editor of Hadassah Magazine (originally Hadassah Newsletter) from 1947 to 1980.

This record group consists of printed materials and publications, produced by Hadassah projects and departments, Young Judaea, and other Zionist organizations from 1911-2011. Materials in the record group include periodicals, newsletters, greeting cards, certificates, invitations, brochures, pamphlets, catalogs, and other professionally produced printed materials. Besides Young Judaea, projects documented include Hadassah Magazine, the Hadassah Medical Organization, Youth Aliyah, the Jewish National Fund, and Hadassah Israel Education Services.

The Rahn Family Collection centers on the lives of Alfred and Lilli (née Bechmann) Rahn, but also contains many documents of their parents, siblings, and even more distant family members. It also documents the family members' attempts to receive restitution for their losses. The collection includes a large amount of correspondence, official, personal, and legal documents, photographs and photo albums, financial documentation, manuscripts and fragments of creative and academic writing, family trees and genealogical notes, newspaper clippings, poetry, educational certificates and diplomas, texts of lectures, teaching materials, a few recipes, and other papers.

The Robison Family Fapers reflect various activities of Adolf C. and Ann Green Robison in civic organizations, Jewish communal life, Jewish national and international affairs, and individually in the arts. The collection contains information on the origins of the United Nations; and on aid to Israel before, during, and after the War of Independence. The materials include correspondence, memoranda, minutes, reports, financial documents, newspaper clippings, photographs, diaries, scrapbooks, musical scores, and play scripts.